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Online Advanced Release
Articles appearing in this "Online Advanced Release" section have been peer-reviewed and accepted for publication in the Journal of Refractive Surgery and posted online before print publication. Articles appear on this site after copyediting and author corrections, but before final proofing. The content of the article will usually remain unchanged, and possible further corrections are fairly minor. The final published article will specify the issue and page numbers. Once the final version is available in print, the version posted here will be removed from this site.
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Table of Contents
Multifocal Corneal Ablation for Hyperopic Presbyopes
Seok Won Jung, MD; Min Jung Kim, MS; Shin Hae Park, MD; Choun-Ki Joo MD, PhD
Submitted: 2/21/07; Accepted: 11/7/07; Posted: 4/30/08Using VISX CustomVue system, a corneal profile with a 1.00 diopter near power for presbyopic correction and a paracentral 1.00 diopter near central power for presbyopia correction, and a paracentral correction for distance vision in 54 eyes, the authors demonstrated improved uncorrected distance and near visual acuity with no significant change in higher order aberrations 6 months after surgery in 27 hyperopic patients.
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Fabricio Witzel de Medeiros, MD; Rajiv R. Mohan, PhD; Chikako Suto, MD; Sunilima Sinhá, BA; Vera L. Bonilha, PhD; Shyam S. Chaurasia, PhD; Steven E. Wilson, MD
Submitted: 7/5/07; Accepted: 11/7/07; Posted: 4/30/08In rabbits, there was no difference in clinical haze or the generation of myofibroblasts in the anterior stroma between mechanical removal of the epithelium and removal using 20% ethanol for 30 seconds.
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Dan Z. Reinstein, MD, MA(Cantab), FRCSC, FRCOphth; Timothy J. Archer, MA(Oxon), DipCompSci(Cantab); Marine Gobbe, MST(Optom), PhD; Ronald H. Silverman, PhD; D. Jackson Coleman, MD
Submitted: 6/21/07; Accepted: 11/20/07; Posted: 4/30/08In 110 normal myopic human eyes, very high-frequency digital ultrasound scanning determined the three-dimensional profile of the epithelial thickness, with a vertex mean of 53 µm, with the inferior epithelium being approximately 5 µm thicker.
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Seven-year Follow-up of LASIK for Moderate to Severe Myopia
Zhaoqiang Liu, MD, PhD; Yan Li, MD; Zhenying Cheng, MD; Fang Zhou, MD; Hua Jiang, MD; Jinghai Li, MD
Submitted: 1/26/07; Accepted: 11/27/07; Posted: 4/30/08Of an original cohort of 75 consecutive patients, 79% were evaluated at 7 years after LASIK for myopia. Mean refraction remained stable from 1 to 7 years and no progressive late-onset complications occurred.
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Ramon C. Ghanem, MD; Vinicius C. Ghanem, MD; Denise C. de Souza, MD; Newton Kara-José, MD, PhD; Emir A. Ghanem, MD
Submitted: 5/25/07; Accepted: 11/27/07; Posted: 4/30/08In a series of 19 consecutive eyes that previously had radial keratotomy and developed hyperopia, measurements were taken and topography-guided photorefractive keratectomy for hyperopia and astigmatism was done using the MEL-70 platform, with the use of mitomycin C. Preoperative spherical equivalent refraction was +3.80±2.47 D and at 12 months postoperative, it was –3.33±1.96 D.
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Acular LS for Control of Pain Before and During LASIK: A Randomized, Masked Contralateral Eye Trial
Paul J. Dougherty, MD
Submitted: 7/11/07; Accepted: 1/4/08; Posted: 4/30/08Using an ocular pain severity scale of 0 to 6 (extremely painful), and applying Acular LS and artificial tears in a contralateral, masked eye trial before and during surgery, a resultant mean pain score of 0.53 in the Acular LS group and 1.23 in the tears group showed a statistically significant reduction in pain.
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LASIK for Myopia of –9.00 to –17.00 D With the VISX STAR S2: 2- to 5-year Follow-up
Nina Lindbohm, MD, PhD; Ilpo S. Tuisku, MD; Timo M. Tervo, MD, PhD
Submitted: 2/19/07; Accepted: 1/4/08; Posted: 4/30/08LASIK to treat myopia of –9.00 to –17.00 D demonstrated a spherical equivalent refraction postoperatively within 1.00 D for 40% of eyes and 2.00 D for 70%, with high levels of patient satisfaction at 2 to 5 years.
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Bruno M. Fontes, MD; Renato Ambrósio, Jr, MD, PhD; Ruiz S. Alonso, MD; Daniela Jardim, MD; Guillermo C. Velarde, DSc; Walton Nosé, MD
Submitted: 3/15/07; Accepted: 9/19/07; Posted: 4/30/08In a series of 150 consecutive patients, corneal hysteresis increased with corneal thickness and decreased with increasing age.
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Matthew B. McCauley, MD; Daniel M. Anderson, MS; Anthony J. Johnson, MD
Submitted: 12/4/07; Accepted: 2/27/08; Posted: 4/30/08The authors report the first case of combat trauma in a patient implanted with bilateral phakic ICLs, emphasizing the importance of eye protection.
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A Prospective Bilateral Comparison of Epi-LASIK and LASEK for Myopia
Ahmet Hondur, MD; Kamil Bilgihan, MD; Berati Hasanreisoglu, MD
Submitted: 6/21/07; Accepted: 11/20/07; Posted: 4/15/08In a series of 25 patients, epi-LASIK was done in one and eye and LASEK in the other eye for myopia, with no differences in the postoperative outcomes.
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Ali A. Mearza, FRCOphth; Mohammed Muhtaseb, FRCOphth; Ioannis M. Aslanides, PhD
Submitted: 4/3/07; Accepted: 11/7/07; Posted: 4/15/08A prospective contralateral eye study in 22 patients showed similar refractive and visual acuity outcomes with the WaveLight ALLEGRETTO WAVE Eye-Q and the SCHWIND ESIRIS excimer lasers for myopia and hyperopia.
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Effect of Thin Femtosecond LASIK Flaps on Corneal Sensitivity and Tear Function
Irina S. Barequet, MD; Ami Hirsh, MD; Samuel Levinger, MD
Submitted: 5/13/07; Accepted: 11/7/07; Posted: 4/15/08In a series of 72 myopic eyes undergoing LASIK with an IntraLase femtosecond laser creating an approximately 100-µm thick flap and a Bausch & Lomb excimer laser, therewas minimal change in central corneal sensitivity and tear function over 6 months postoperatively compared to baseline.
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Vinícius Coral Ghanem, MD; Newton Kara-José, MD; Ramon Coral Ghanem, MD; Samuel Angelo Coral, MD
Submitted: 11/8/06; Accepted: 8/18/07; Posted: 4/15/08In a contralateral eye study, 51 patients received PRK in one eye and LASEK in the other eye. Patients preferred the PRK eye through approximately 1 month postoperatively with no significant difference thereafter. No significant differences were found in refractive or visual acuity outcomes after 2 weeks.
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Paul J. Dougherty, MD; Harkaran S. Bains
Submitted: 10/20/06; Accepted: 11/7/07; Posted: 3/31/08In a retrospective comparison of approximately 100 myopic eyes each for the NIDEK scanning-slit, VISX S4 CustomVue, and the Alcon CustomCornea in 2003 demonstrated no differences in refractive or visual acuity outcomes.
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Measurement of LASIK Flap Thickness With Anterior Segment Optical Coherence Tomography
Arthur C.K. Cheng, MRCS, FCOphth(HK); Thomas Ho, MRCOphth; Silvania Lau, BSc; Amy L. Wong, MRCS; Chris Leung, MD; Dennis S.C. Lam, MD, FRCS, FRCOphth
Submitted: 4/5/07; Accepted: 11/7/07; Posted: 3/31/08In a series of 39 eyes undergoing LASIK, intraoperative ultrasound measurement of LASIK flap thickness was significantly thinner than postoperative LASIK flap measurement with OCT.
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Seung Ah Chung, MD; Eung Kweon Kim, MD, PhD; IK Hee Ryu, MD; Jin Kook Kim, MD, PhD; Hyung Keun Lee, MD, PhD
Submitted: 1/15/07; Accepted: 11/7/07; Posted: 3/31/08A series of 204 eyes treated with PRK had immediate postoperative coverage of the cornea with a therapeutic soft contact lens, cultured sheet epidermal allogeneic keratinocytes, or CEAK with amniotic membrane strips. Although the CEAK-covered corneas demonstrated faster epithelial healing, there was no clinically significant difference in patient outcomes among the three groups.
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Comparison of the AcrySof IQ Aspheric Blue Light Filter and the AcrySof SA60AT Intraocular Lenses
Ulrich Mester, MD; Hakan Kaymak, MD
Submitted: 9/5/06; Accepted: 9/5/07; Posted: 3/14/08In a prospective comparison of the spherical AcrySof SA60AT to the aspheric SN60WF demonstrated statistically significantly less total higher order aberrations for a 5-mm pupil in the aspheric lens with a significant reduction in spherical aberration and increased area under the constrast sensitivity curve.
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Arthur C.K. Cheng, MRCS, FCOphth(HK); Thomas Ho, MRCOphth; Srinivas K. Rao, FRCS;
Submitted: 7/25/06; Accepted: 9/7/07; Posted: 3/14/08Using the Orbscan II to measure posterior corneal curvature in 194 eyes before and after myopic LASIK in an area outside of the laser treatment, the peripheral zone shows no difference between preoperative and postoperative values.
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Gerard Sutton, FRANZCO, FRACS, MBBS; Chris Hodge, BAppSc(Orth)
Submitted: 9/26/06; Accepted: 9/12/07; Posted: 3/14/08In a series of 141 eyes using the 30-KHz IntraLase femtosecond laser to make a LASIK flap, 98% of flaps were within 620 µm of intended thickness and 70% were within 610 µm.
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Comparison of the Toric Implantable Collamer Lens and Custom Ablation LASIK for Myopic Astigmatism
Donald R. Sanders, MD, PhD; Monica L. Sanders, BS
Submitted: 3/20/07; Accepted: 9/19/07; Posted: 3/14/08Using United States Food and Drug Administration data, a comparison of the Toric Implantable Collamer Lens with custom ablation LASIK using the VISX and Alcon lasers demonstrated similar refractive outcomes in all groups, ranging from –3.00 to –11.00 diopters at baseline.
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Aleksandar Stojanovic, MD; Ling Wang, MD, MS; Mirko R. Jankov, MD, PhD; Tore A. Nitter, MD, PhD; Qinmei Wang, MD
Submitted: 2/26/07; Accepted: 11/7/07; Posted: 3/14/08Using the WaveLight ALLEGRETTO laser with wavefront optimized ablation in 46 eyes and the Custom-Q ablation in 42 eyes for the treatment of myopia from approximately –1.00 to –8.00 D, the clincial outcomes were the same in both groups, except for a mean postoperative asphericity closer to preoperative values in the Custom-Q group.
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Aylin Ertan, MD; Humeyra Karacal, MD
Submitted: 4/15/07; Accepted: 11/7/07; Posted: 3/14/08In a retrospective series of 133 eyes using the IntraLase femtosecond laser to create a LASIK flap or tunnels for INTACS, mean temporal decentration was approximately 0.60 mm in the LASIK group and 0.79 mm in the INTACS group, as measured by the Pentacam.
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Alejandro Cerviño, OD, PhD, MCOptom; Sarah L. Hosking, BSc(Hns), PhD MCOptom, FAAO, DBO; Robert Montés-Micó, OD, MPhil, PhD
Submitted: 4/29/07; Accepted: 11/7/07; Posted: 3/14/08In a series of 80 myopic eyes measured under non-cycloplegic conditions with a 5-mm pupil, the higher order aberrations reported by the NIDEK OPD-Scan and the Zeiss WASCA aberrometers showed significant differences for specific higher order aberrations, suggesting the instruments cannot be used interchangeably.
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Central Serous Chorioretinopathy Following LASIK for Hyperopia
Marcus C.C. Lim, MA, MB, BChir, MRCSEd; Tat-Keong Chan, MBBS, FRCSEd
Submitted: 2/27/07; Accepted: 11/20/07; Posted: 3/14/08A 50-year-old man developed central serous chorioretinopathy after unilateral LASIK for hyperopia.
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Regularity of Human Corneal Flaps Prepared by Femtosecond Laser Technology
Urs Vossmerbaeumer, MD, MSc; Jost B. Jonas, MD
Submitted: 8/17/05; Accepted: 11/7/07; Posted: 3/14/08Uniform evenness of corneal flap thickness after LASIK with a femtosecond laser was assessed histomorphometrically in five human donor eyes.
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Vinícius C. Ghanem, MD; Giselle C. Souza, MD; Denise C. Souza, MD; Juliana M.Z. Viese, MD; Sarah L.P. Weber, MD; Newton Kara-José, MD, PhD
Submitted: 12/21/06; Accepted: 7/6/07; Posted: 2/29/08In a prospective, randomized, contralateral comparison of photorefractive keratectomy in one eye and butterfly LASEK in the other, eyes with PRK had faster corneal epithelial healing and less pain postoperatively.
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Synergistic Effect of Ethanol and Mitomycin C on Corneal Stroma
Marcelo V. Netto, MD; Jackson Barreto, Jr, MD; Ruth Santo, MD, PhD; Samir Bechara, MD; Newton Kara-Jose, MD; Steven E. Wilson, MD
Submitted: 1/6/07; Accepted: 7/10/07; Posted: 1/31/08Rabbit corneas were treated with ethanol solution to facilitate epithelial removal prior to PRK with mitomycin C with a significant decrease in keratocytes density in the anterior stroma compared to corneas that had manual epithelial removal prior to PRK with MMC.
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Bao-Gui Wang, MD; Chris P. Lohmann, MD, PhD; Iris Riemann, PhD; Harald Schubert, PhD; Karl-Juergen Halbhuber, MD; Karsten König, PhD
Submitted: 5/4/06; Accepted: 8/13/07; Posted: 1/31/08A solid-state Ti:sapphire femtosecond nanojoule laser created corneal flaps and lenticules in rabbits.
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Fabrizio Casprini, MD, PhD; Angelo Balestrazzi, MD, PhD; Gian Marco Tosi, MD, PhD; Marco Lazzarotto, MD; Alex Malandrini, MD; Francesca Lepri, MD; Gianluca Martone, MD; Tomaso Caporossi, MD; Aldo Caporossi, MD
Submitted 9/6/06; Accepted: 9/5/07; Posted: 1/31/08After Nd:YAG posterior capsulotomy, higher order optical aberrations were greater than those in control eyes with an intact capsule and no opacification.
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Influence of Age on Ocular Wavefront Aberration Changes With Accommodation
Yoshihiko Iida, MD; Kimiya Shimizu, MD; Misae Ito, CO; Masanobu Suzuki, MD
Submitted: 11/28/06; Accepted: 9/5/07; Posted: 1/31/08Accommodation induces increased higher order aberrations, especially in patients aged 20 to 29, especially spherical aberration. Less change was seen between age 30 and 49.
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Long-term Endothelial Cell Loss After Traumatic Dislocation and Repositioning of Artisan Phakic IOL
Ugo de Sanctis, MD, PhD; Bernardo Mutani, MD; Federico M. Grignolo, MD, PhD
Submitted: 1/29/07; Accepted: 11/7/07; Posted: 1/31/08Progressive and long-term endothelial cell loss after repositioning of posttraumatically dislocated Artisan PIOL is comparable to eyes with uneventful implantation.
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Jaime Javaloy, MD, PhD; Carlos Barrera, MD; Gonzalo Muñoz, MD, PhD; Juan J. Pérez-Santonja, MD, PhD; María T. Vidal, MD, PhD; Jorge L. Alió, MD, PhD
Submitted: 6/13/07; Accepted: 11/7/07; Posted: 1/31/08A 32-year-old man developed recurrent, late-onset diffuse lamellar keratitis after LASIK due to Cogan's syndrome.
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Microbial Keratitis After INTACS Implantation With Loose Suture
Hasan Hashemi, MD; Reza Ghaffari, MD; Masood Mohammadi, MD; Sasan Moghimi, MD; Mohammad Miraftaab, MD
Submitted: 3/28/07; Accepted: 9/12/07; Posted: 1/15/08Occurrence of infectious keratitis (Staphyloccocus aureus) after INTACS implantation due to loose suture.
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Shady T. Awwad, MD; Dorotheea Warmerdam, MD; R. Wayne Bowman, MD; Surendar Dwarakanathan, MD; H. Dwight Cavanagh, MD, PhD; James P. McCulley, MD
Submitted: 2/26/07; Accepted: 7/23/07; Posted: 1/15/08The aspheric AcrySof IQ had less total order and spherical aberration and improved contrast sensitivity compared to the spherical AcrySof Natural IOL.
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Comparison of Intacs Treatment Outcomes With Femtosecond Laser in Patients With Keratoconus
Aylin Ertan, MD; Ersel Ozkilic, MD
Submtted: 3/11/07; Accepted: 7/23/07; Posted: 1/15/08In a series of 109 eyes with keratoconus ranging from age 13 to 56 years, Intacs implantation showed no differences in corneal flattening or refractive and visual outcome based on age.
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Vijay Savant, FRCS(Ed), MRCOpth; Randhir Chavan, MRCOphth; Sreekumari Pushpoth, MRCOphth; B. Ilango, FRCOphth
Submitted: 12/25/06; Accepted: 7/10/07; Posted: 1/15/08In a series of 50 normal eyes, anterior chamber depth measured by the IOL Master gave a mean of 3.23 mm and by the Pentacam a mean of 3.21 mm. The instruments can be used interchangeably for this purpose.
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Jenn-Chyuan Wang, FRCS (Ophth); Catey Bunce, MSc; Hung-Ming Lee, FRCS (Ed)
Submitted: 4/11/06; Accepted: 7/9/07; Posted: 1/15/08In a series of 48 eyes undergoing LASIK, central corneal thickness was measured immediately prior to surgery with a mean value of 559 µm by ultrasound pachymetry and 521 µm by online OCP. The repeatability of both instruments was good.
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Donald R. Sanders, MD, PhD
Submitted: 2/15/07; Accepted: 5/9/07; Posted: 12/28/07In an FDA trial of the STAAR Visian Implantable Collamer Lens (model V4) in 526 eyes, a follow-up of 3 to 7 years demonstrate 7% of eyes developed subepithelial opacities and 2% developed a clinically significant cataract.
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Intrasubject Corneal Thickness Asymmetry
Stephen S. Khachikian, MD; Michael W. Belin, MD; Joseph B. Ciolino, MD
Submitted: 11/20/06; Accepted: 5/28/07; Posted: 12/28/07Average central corneal thickness reading with the Pentacam rotating Schiempflug slit camera in 1448 eyes of 724 consecutive patients was 539 µm, with an average difference between right and left eyes of 9 µm.
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Geunyoung Yoon, PhD; Seth Pantanelli, MS; Scott MacRae, MD
Submitted: 1/24/07; Accepted: 6/15/07; Posted: 12/28/07Using the Schiempflug slit topography of the Orbscan IIz to generate elevation maps, both Zernike and Fourier reconstruction algorithms were used to reconstruct the original maps for normal, keratoconus, penetrating keratoplasty, and postoperative LASIK eyes. The Zernike reconstruction up to the 5th order produced more accurate values than the iterative Fourier algorithms.
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Association Between Ocular Dominance and Refraction
Ilker Eser, MD; Daniel S. Durrie, MD; Frank Schwendeman, OD; Jason E. Stahl, MD
Submitted: 3/30/07; Accepted: 5/9/07; Posted: 12/28/07In a retrospective study of 2453 consecutive patients, 67% were right-eye dominant. There was no correlation between spherical equivalent refractive error and ocular dominance.
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Wavefront-guided Custom Ablation for Myopia Using the NIDEK NAVEX Laser System
Jan Venter, MD
Submitted 10/16/06; Accepted 4/24/07; Posted 11/15/07In a series of 120 myopic eyes treated with the NIDEK wavefront-guided custom ablation (OPDCAT) and followed for a mean of 10 months, 92% had a spherical equivalent refraction within ±0.50 D. Eyes with preoperative higher order aberrations RMS >0.30 µm are more likely to have reduction in higher order aberrations.
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Measure of Keratoconus Progression Using Orbscan II
Hyojin Kim, PhD; Choun-Ki Joo, MD, PhD
Submitted 8/11/05; Accepted 6/2/07; Posted 11/15/07In a series of 56 eyes of 35 patients with a clinical diagnosis of keratoconus, 30 eyes showed a progression with a mean rate of change of steepening of the cornea of 11.37 D for a half-year, and 26 eyes did not demonstrate progression with a rate of change of 0.15 D per half-year. Risk factors for progression included eye rubbing, inferior steepening on corneal topography, and contact lens wear.
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Roberto Pinelli, MD; Dolores Ortiz, PhD; Anna Simonetto, MA; Cristian Bacchi, OD; Esperanza Sala, OD; Jorge L. Alió, MD, PhD
Submitted 9/13/06; Accepted 3/16/07; Posted: 10/31/07Using a Technolas 217z laser, a four-zone peripheral multifocal LASIK ablation pattern is used to create a multifocal cornea known as "peripheral presbyLASIK." In 22 hyperopes treated bilaterally, mean binocular uncorrected visual acuity was 1.06 for distance and 0.84 for near, with a mean postoperative spherical equivalent refraction of –0.42 D.
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Comparison Between LASEK With Mitomycin C and LASIK for the Correction of Myopia of 7.00 to 13.75 D
Laura de Benito-Llopis, MD; Miguel A. Teus, MD, PhD; Jose M. Sánchez-Pina, DO
Submitted: 12/18/06; Accepted 5/16/07; Posted: 10/31/07In a matched series of 114 eyes in each group comparing LASEK with mitomycin C and LASIK, a refractive outcome of ±0.50 D was achieved at 1 year in 68% of LASEK and 79% of LASIK eyes. Uncorrected visual acuity was consistently better in LASIK eyes for the first 3 months than in LASEK eyes.
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Phakic Refractive Lens: Two-year Results
Annemari Koivula, MD; Mikaela Taube, RN; Charlotta Zetterström, MD, PhD
Submitted: 5/24/06; Accepted: 5/16/07; Posted: 10/31/07In a series of 14 myopic and 16 hyperopic eyes with a posterior chamber plate phakic refractive lens implanted and followed for 2 years, the uncorrected visual acuity was 20/20 or better in 8 (40%) of eyes. Lens rotation of 10° to 87° occurred in 20% of eyes after 3 months, and the mean distance between the PRL and the crystalline lens decreased from a mean of 0.47 mm at 3 months to a mean of 0.27 mm at 2 years. No cataracts were reported.
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Retinal Nerve Fiber Layer Measurements Before and After Photorefractive Keratectomy
Michele Iester, MD, PhD; Fabio De Feo, MD; Graziano Bricola, MD; Marina Papadia, MD; GianMaria Venturino, MD; Carlo E. Traverso, MD; Giovanni Calabria, MD, PhD
Submitted: 8/16/06; Accepted: 5/1/07; Posted: 10/15/07Photorefractive keratectomy changes the accuracy of scanning laser polarimetry and measurements of the of the nerve fiber layer thickness of the retina.
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The Effect of Cyclosporine A (Restasis) on Recovery of Visual Acuity Following LASIK
Roxana Ursea, MD; Tracy L. Purcell, PhD; Bryan U. Tan, MD; Aniruddha Nalgirkar, MD; Mario E. Lovaton, MD; Michael P. Ehrenhaus, MD; David J. Schanzlin, MD
Submitted: 8/17/06; Accepted 4/24/07; Posted: 10/15/07In a retrospective, non-randomized comparison of standard (20 patients) postoperative therapy to the additional use of topical Restasis (25 patients) twice daily, visual acuity returned more rapidly in the patients receiving Restasis.
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Uzeyir Erdem, MD; Orkun Muftuoglu, MD; Fatih Çakir Gundogan, MD; Gungor Sobaci, MD; Atilla Bayer, MD
Submitted 10/11/06; Accepted 4/24/07; Posted: 9/17/07The mean distance from the coaxially sighted corneal light reflex to the center of the pupil is approximately 0.3 mm in myopes and 0.45 mm in hyperopes, usually in a temporal direction.
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LASIK in Children With Hyperopic Anisometropic Amblyopia
Canan Asli Utine, MD, MSc; Hanefi Cakir, MD; Abdulkadir Egemenoglu, MD; Irfan Perente, MD
Submitted 10/7/06; Accepted 3/28/07; Posted: 8/30/07Thirty-two children with hyperopic anisometropic amblyopia ranging in age from 4 to 15 years, hyperopic LASIK was done on the amblyopic eye, improving the uncorrected visual acuity from 0.06 preoperatively to 0.27 postoperatively and the spherical equivalent refraction from a mean uncorrected visual acuity of +5.17 preoperatively to a mean of +1.39 postoperatively (to balance out the unoperated hyperopic other eye).
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Recalcitrant Epithelial Ingrowth in Patients With Compromised Eyelid Function
David B. Samimi, BA; D. Rex Hamilton, MD, MS
Submitted: 1/18/07; Accepted: 4/9/07; Posted 8/30/07Two patients with weak eyelid closure developed unilateral epithelial ingrowth after LASIK. Weak eyelid closure may be a predisposing factor to poor flap adhesion and epithelial ingrowth.
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George D. Kymionis, MD, PhD; Vasilios F. Diakonis, MD; Spyridon Charisis, MD; Aristofanis I. Pallikaris, PhD; Dimitrios I. Bouzoukis, MD; Sonia H. Yoo, MD; Irine Naoumidi, PhD; Miltiadis K. Tsilimbaris, MD, PhD
Submitted 8/21/06; Accepted 3/19/07; Posted 8/15/07In rabbits that underwent photorefractive keratectomy, application of mitomycin C 0.02% for 2 minutes did not produce histologic damage to the ciliary body or changes in intraocular pressure.
[Read more]
Arthur C.K. Cheng, MRCS, FCOphth(HK); Srinivas S.K. Rao, FRCS; Silvania Lau, BSc; Amy Wong, MRCS; Dennis S.C. Lam, FRCS, FRCOphth
Submitted 7/5/06; Accepted 3/16/07; Posted 8/15/07Using eight different methods to calculate the mean corneal power after myopic LASIK, the Gaussian optics formula and the Wang method (modified after Maloney) yielded results most comparable with the clinical history method.
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Effect of Flap Thickness on Higher Order Wavefront Aberrations Induced by LASIK: A Bilateral Study
Zhen-Ying Cheng, MD, PhD; Ji C. He, PhD; Xing-Tao Zhou, MD, PhD; Ren-Yuan Chu, MD
Submitted 10/18/06; Accepted 3/6/07; Posted 7/16/07In a right eye/left eye study of 28 patients, there was no difference in changes in higher order aberrations between thick LASIK flaps and thin LASIK flaps.
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Custom-designed Toric Phakic Intraocular Lenses to Correct High Corneal Astigmatism
Erik L. Mertens, MD, FEBO; Donald R. Sanders, MD, PhD; Pauline N. Vitale, BS
Submitted 11/19/06; Accepted 5/1/07; Posted 7/16/07A patient with a preoperative manifest refractive cylinder of approximately 5.00 diopters in each eye received custom-made toric Implantable Collamer Lenses (ICL, STAAR), which reduced her manifest refractive cylinder to 0.50 D.
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