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ISRS: International Society of Refractive Surgery

Chang, Mastering Refractive IOLs

Original Articles:
Laserinterferometric Measurements of Accommodative Changes in the Position of an Optic-shift Intraocular Lens

Journal of Refractive Surgery  Vol. 25   No. 5   May 2009

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Detlef Uthoff, MD, FSES, FABI; Detlef Holland, MD; Daniel Hepper; Amit Gulati, PhD; Lioba Koch, OD and Wolfgang Haigis, MS, PhD

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PURPOSE

To measure optically and pharmacologically induced movement of an optic-shift intraocular lens (HumanOptics 1CU).

METHODS

The change in position as well as the accommodative effect of the 1CU was determined using an anterior chamber laser interferometer (Zeiss ACMaster) in 15 eyes of 9 patients. Accommodation was induced by optical stimulus and pharmacologically by pilocarpine 2%.

RESULTS

The mean forward movement due to optical-induced accommodation stimulation was 5±14 µm (range: –10 to +40 µm). Pharmacological stimulation with 2% pilocarpine caused mean anterior movements of 93±162 µm (range: –321 to +402 µm).

CONCLUSIONS

A maximum accommodative effect of 0.50 diopters was measured with this method. This relatively small accommodative effect of the 1CU is in agreement with other studies. Pharmacologically induced optic shift differs significantly from optically induced shift and allows no conclusion on a clinically expected accommodative effect. [J Refract Surg. 2009;25:416-420.]
DOI:10.9999/1081597X-20090422-03

AUTHORS

From Eye Hospital Bellevue, Kiel (Uthoff, Holland, Hepper, Gulati); University of Applied Sciences, Jena (Koch); and University Eye Hospital, Würzburg (Haigis), Germany.

The authors have no financial or proprietary interest in the materials presented herein.

Correspondence: Detlef Uthoff, MD, FSES, FABI, Eye Hospital Bellevue, Lindenallee 21, 24105 Kiel, Germany. Tel: 49 431 301080; Fax: 49 431 3010840; E-mail: uthoff@augenklinik-bellevue.de

Received: July 17, 2006; Accepted: June 10, 2008

Posted online: August 15, 2008

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